| 产品详情 |
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| Antigenic Specificity | XBP-1s |
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| Clone | 143F |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), Immunofluorescence Microscopy (IF), IHC |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-XBP-1s. XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of its ability to bind X-box, a conserved transcriptional element in the promoter of human HLA DR gene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is also essential for differentiation of plasma cells. XBP-1 upregulates as part of the ER stress response, also known as the unfolded protein response. Unspliced XBP-1 is 261 amino acids and migrates on the SDS-PAGE around 33 kD; spliced XBP-1, recognized by clone 143F, is 371 amino acids and migrates around 55 kD. |
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| Immunogen | XBP-1s recombinant protein |
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| Other Names | X-box binding protein 1 |
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| Gene, Accession # | Gene ID: 7494 |
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| Catalog # | 647501 |
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| Price | |
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| Order / More Info | XBP-1s Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 17298185,20548102,21138840,21159797,21349849,21447826,22337954,22431749,22679299,23926301,24982422 |
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