产品详情 |
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Antigenic Specificity | WAVE1 |
Clone | K91/36 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | peroxidase (HRP) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HRP anti-WAVE1. Organ morphogenesis can occur through cellular response to extracellular signals that alter actin dynamics. Wiskott-Aldrich syndrome protein-family verprolin homologous protein 1 (WAVE1) is an actin-interacting protein involved in brain morphogenesis. WAVE1 interacts with Arp (actin-related proteins) 2/3 to regulate the cytoskeleton. WAVE proteins mediate lamellipodia formation and are critical for normal CNS myelination. WAVE1 can be phosphorylated by Cdk5 to downregulate Arp2/3 complex-dependent actin polymerization. |
Immunogen | This monoclonal antibody was raised against a synthetic peptide corresponding to amino acids 477-498 of human Wave1/Wasp family 1 protein. |
Other Names | Wiskott-Aldrich syndrome protein family member 1, protein WAVE-1, WASP family protein member 1, homology of dictyostelium scar 1, verprolin homology domain-containing protein 1, MMS-5208-100 |
Gene, Accession # | Gene ID: 8936 |
Catalog # | 817904 |
Price | |
Order / More Info | WAVE1 Antibody from BIOLEGEND |
Product Specific References | n/a |
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