产品详情 |
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Antigenic Specificity | Vimentin |
Clone | W16220A |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence Microscopy (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Vimentin. Vimentin are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is a widely expressed and highly conserved 54 kD protein that is constitutively expressed in mesenchymal cells, endothelial cells lining blood vessels, renal tubular cells, macrophages, neutrophils, fibroblasts, and leukocytes1,2. Vimentin is used as a marker of mesenchymal cells to distinguish them from epithelial cells3. Increased vimentin expression is frequently used as an EMT marker in cancer4. Autoantibodies to vimentin are commonly found in patients with autoimmune diseases such as Lupus5 and rheumatoid arthritis6, and also found after transplantation7. |
Immunogen | Partial mouse Vimentin (224-446 a.a.) recombinant protein expressed in E. coli. |
Other Names | Vim, CTRCT30, HEL 113, Epididymis Luminal Protein 113 |
Gene, Accession # | Gene ID: 22352 |
Catalog # | 699302 |
Price | |
Order / More Info | Vimentin Antibody from BIOLEGEND |
Product Specific References | n/a |
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