产品详情 |
Edit |   |
Antigenic Specificity | CD66d/e |
Clone | 308/3-3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-human CD66d/e. The 308/3-3 mAb reacts with an antigen epitope shared by CD66d and e. CD66d/e are members of the CEA (carcinoembryonic antigen) family of the Ig superfamily. CD66 plays a role in hemophilic and heterophilic adhesion. CD66d is a major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neisseria, Moraxella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis. CD66e molecule is also called CEA or CEACAM5, and is primarily found on epithelial cells. CD66e binds to CD66a, c and e. |
Immunogen | Recombinant soluble human CEACAM3-Fc produced in HEK293 cells |
Other Names | CEACAM3, CGM1, CEACAM5, CEA |
Gene, Accession # | Gene ID: 1084, 1048 |
Catalog # | 392806 |
Price | |
Order / More Info | CD66d/e Antibody from BIOLEGEND |
Product Specific References | n/a |
产品资料 |
|
|