| 产品详情 |
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| Antigenic Specificity | FcRL4 |
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| Clone | 413D12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b, κ |
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| Format | PE-Cy7 conjugate |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE/Cy7 anti-human CD307d (FcRL4). FcRL4 (Fc receptor-like 4) is a 57 kD single pass type I transmembrane protein that exhibits 4 Ig like C2 domains. Also known as ITRA1, IGFP2, and FcRH4, FcRL4 is predominately found on a subset of memory B cells. Activation of FcRL4 contributes to B cell receptor inhibition through activation of the tyrosine kinases SHP-1 and 2. FcRL4's nascent loci is 1q23.1; however, breakpoint mutations are associated with multiple myeloma and non-Hodgkins lymphoma. Increased FcRL4 expression on memory B cells has also been observed in HIV viremic patients. FcRL4 predominately binds aggregated IgA, binds weakly with IgG3 and IgG4, and does not bind IgG1 and IgG2. |
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| Immunogen | P815 cells transfected with FcRL4 |
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| Other Names | FcRL4 (Fc receptor-like 4), IRTA1, IGFP2 |
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| Gene, Accession # | Gene ID: 83417 |
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| Catalog # | 340208 |
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| Price | |
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| Order / More Info | FcRL4 Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 21908428 |
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