| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD354 |
|---|
| Clone | TREM-26 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human, African green, baboon, cynomolgus, rhesus |
|---|
| Isotype | IgG1, κ |
|---|
| Format | biotin conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry (FC), ELISA Detection |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Biotin anti-human CD354 (TREM-1). TREM-1 is a 30 kD glycoprotein also known as triggering receptor expressed on myeloid cells 1, and triggering receptor expressed on monocytes 1. It is a Type I membrane protein that contains an immunoglobulin-like V-type domain. Alternatively spliced protein variant may be secreted. TREM-1 is highly expressed on peripheral blood myeloid cells (particularly mature monocytes and granulocytes); TREM-1 expression can be further upregulated by bacteria, fungi and lipopolysaccharide. TREM-1 has been shown to interact with the adaptor protein DAP12 to stimulate neutrophil and monocyte-mediated inflammatory responses through the triggering and release of pro-inflammatory cytokines and chemokines. TREM-1 is thought to amplify inflammatory responses to fungal and bacterial infections and potentiate septic shock. This antibody has been shown to be useful for flow cytometry and activation of monocytes and granulocytes. |
|---|
| Immunogen | Recombinant human TREM-1 |
|---|
| Other Names | Triggering receptor expressed on myeloid cells 1, triggering receptor expressed on monocytes 1 |
|---|
| Gene, Accession # | Gene ID: 54210 |
|---|
| Catalog # | 314904 |
|---|
| Price | |
|---|
| Order / More Info | CD354 Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|