产品详情 |
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Antigenic Specificity | CD37 |
Clone | Duno85 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse CD37. CD37, also known as Tspan26 is a 40-60 kD member of the tetraspanin (TM4SF) family, with two extracellular regions and both termini in the cytoplasm. CD37 is highly expressed on mature B cells and is also expressed on T cells, monocytes, macrophages, and neutrophils, and dendritic cells to a lesser extent. CD37 forms complexes in the cell membrane with CD53, CD81, CD82, MHC class II and dectin 1. CD37 is essential for B cell survival, regulates T cell proliferation, IgA production, and is involved in dendritic cell migration. CD37 has been described as a promising target in the treatment of B cell malignancies. |
Immunogen | Expression vector containing full length mouse CD37 gene |
Other Names | Tspan26, Tetraspanin-26 |
Gene, Accession # | Gene ID: 12493 |
Catalog # | 146202 |
Price | |
Order / More Info | CD37 Antibody from BIOLEGEND |
Product Specific References | n/a |
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