产品详情 |
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Antigenic Specificity | CD44H |
Clone | OX-49 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | IgG2a, κ |
Format | fluorescein (FITC) conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FITC anti-rat CD44H (Pgp-1, H-CAM). CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope. |
Immunogen | Rat T blasts from mixed lymphocyte reactions |
Other Names | Pgp-1, H-CAM |
Gene, Accession # | Gene ID: 12505 |
Catalog # | 203906 |
Price | |
Order / More Info | CD44H Antibody from BIOLEGEND |
Product Specific References | n/a |
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