| 产品详情 |
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| Product Name | GSK864 |
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| Description | An inhibitor of mutant IDH1 (IC50s = 9, 15, and 17 nM for IDH1 mutants R132C, R132H, and R132G, respectively); causes a dose-dependent reduction in 2-hydroxyglutarate and overcomes the block of differentiation in AML cells expressing mutant IDH1 |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | GSK-864 mutant isocitrate dehydrogenase IDH1 IDH-1 wild-type 2-hydroxyglutarate 2-hydroxy glutarate acute myeloid leukemia AML leukemic R132C R132H R132G SGC structural genomics consortium |
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| Gene, Accession, CAS # | CAS: 1816331-66-4 |
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| Catalog # | 18762-1 |
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| Price | |
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| Order / More Info | GSK864 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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