产品详情 |
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Antigenic Specificity | Factor H |
Clone | L20/3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | biotin conjugate |
Size | 500 µg |
Concentration | n/a |
Applications | ELISA Detection, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Biotin anti-human Factor H. Factor H, a 155 kD soluble glycoprotein, is a member of the regulators of complement activation family and is a complement control protein. It circulates in human plasma at a concentration of 500-800 mg/ml that provides critical negative regulation to the alternative pathway of complement cascade. Factor H is secreted by Kupffer cells, hepatocytes, vascular endothelial cells, and platelets. Overactive factor H may result in reduced complement activity on pathogenic cells, increasing susceptibility to microbial infections. Underactive factor H may result in increased complement activity on healthy host cells, resulting in autoimmune diseases. |
Immunogen | Human Complement Factor H |
Other Names | Complement Factor H |
Gene, Accession # | Gene ID: 3075 |
Catalog # | 518504 |
Price | |
Order / More Info | Factor H Antibody from BIOLEGEND |
Product Specific References | n/a |
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