| 产品详情 |
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| Antigenic Specificity | ERK1 |
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| Clone | W15133A |
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| Host Species | Rat |
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| Reactive Species | human, mouse |
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| Isotype | IgG2a, κ |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot (WB), KO/KD-Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-ERK1. ERK1 is a member of mitogen-activated kinases (MAPKs) of serine/threonine protein kinases. ERK1 and ERK2 share 85% homology and both are involved in the MAP kinase signaling cascade. ERK1/2 can be activated by a range of extracellular stimuli, such as mitogen, growth factors, neurotransmitters, chemokines, and cytokines, through receptor tyrosine kinases (RTK), G protein-coupled receptors (GPCRs), or protein kinase C (PKC). Upon stimulation, ERK1/2 are phosphorylated by the upstream kinase MEK on residues Thr202 and Tyr204 and in turn phosphorylate many other downstream molecules that are involved in a range of cellular processes such as cell proliferation, differentiation, motility and cell death. |
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| Immunogen | Partial human ERK1 recombinant protein (180-379 a.a.) expressed in E. coli. |
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| Other Names | Extracellular signal-regulated kinase 1, Mitogen-activated protein kinase 3 (MAPK3), p44ERK1, p44-MAPK, PRKM3 |
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| Gene, Accession # | Gene ID: 5595 |
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| Catalog # | 687002 |
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| Price | |
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| Order / More Info | ERK1 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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