产品详情 |
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Antigenic Specificity | CD307 |
Clone | 509f6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD307e (FcRL5). FcRL5, also known as CD307e, CD307, IRTA2, FcRH5, and BXMAS1, is a 106 kD type I transmembrane glycoprotein composed of six-eight extracellular Ig like C2 domains and two cytoplasmic ITIM motifs. The FcRL5 gene is located on chromosome 1q21 and is normally expressed by tonsillar plasma cells and germinal center B cells. It has been suggested that FcRL5 contributes to B cell maturation and B cell receptor modulation. The identification of FcRL5 on a number of transformed cell types including hairy cell leukemia, mantle cell lymphoma, chronic lymphocytic lymphoma, and Burkitt’s lymphoma has prompted interest in it as a potential biomarker or target for immunotherapy. FcRL5 binds all aggregated IgG isotypes. |
Immunogen | P815 cells transfected with FcRL5 |
Other Names | CD307, IRTA2, FcRH5, IFGP5, BXMAS1 |
Gene, Accession # | Gene ID: 83416 |
Catalog # | 340302 |
Price | |
Order / More Info | CD307 Antibody from BIOLEGEND |
Product Specific References | n/a |
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