| 产品详情 |
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| Antigenic Specificity | MCM7 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. This MCM7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the N-terminal region of human MCM7. |
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| Immunogen | Human MCM7. |
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| Other Names | CDC47 homolog; P1.1-MCM3; MCM7; CDC47; MCM2; CDABP0042; P1CDC47; P85MCM; PNAS-146; DNA replication licensing factor MCM7 |
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| Gene, Accession # | MCM7, SwissProt: P33993 |
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| Catalog # | abx028737 |
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| Price | |
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| Order / More Info | MCM7 Antibody from ABBEXA |
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| Product Specific References | n/a |
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