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| Antigenic Specificity | ATM (pS1981) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IHC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ATM (pS1981) Antibody is a Rabbit Polyclonal antibody against ATM (pS1981). The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. |
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| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S1981 of human ATM. |
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| Other Names | Ataxia telangiectasia mutated homolog; Ataxia telangiectasia mutated; kinase ATM; AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1; Serine-protein kinase ATM; A-T mutated; AT Mutated; Telomere Maintenance 1; ATM Serine/Threonine Kinase |
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| Gene, Accession # | ATM, Gene ID: 472, SwissProt: Q13315 |
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| Catalog # | abx000358 |
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| Price | |
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| Order / More Info | ATM (pS1981) Antibody from ABBEXA |
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| Product Specific References | n/a |
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