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Product Name | YC-1 |
Description | YC-1 is an NO-independent activator of soluble guanylyl cyclase. It inhibits collagen (10 µg/ml) and thrombin (0.1 U/ml) induced platelet aggregation with IC50 values of 11.7-14.6 and 57.3-59.3 µM, respectively.{4218,4219} In the absence of NO or CO, 200 µM YC-1 increases the activity of purified soluble guanylyl cyclase 12-fold, with an ED50 value of 20 µM.{4220} At a concentration of 200 µM, YC-1 potentiates the maximal activity of soluble guanylyl cyclase in the presence of NO or CO by 40% and >3,000%, respectively. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | activators soluble guanylyl cyclases cyclic cGMP guanylate activation activates yc1 sGC |
Gene, Accession, CAS # | CAS: 170632-47-0 |
Catalog # | 81560-1 |
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Order / More Info | YC-1 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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