产品详情 |
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Product Name | SR 1664 |
Description | A small molecule that blocks phosphorylation of PPARγ by Cdk5 (IC50 = 80 nM; Ki = 28.7 nM) without exhibiting agonist activity at the PPARγ receptor; demonstrates potent, dose-dependent anti-diabetic effects in obese mice without inducing fluid retention and weight gain or inhibiting bone formation |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | antidiabetics PPARγ inhibitors inhibits inhibitions insulin sensitivity Cdk5 cyclin-dependent kinases 5 diabetes obesity obese metabolic syndromes nuclear receptors peroxisomes proliferator-activated receptors γ g gamma .gamma. PPARg PPARgamma PPAR.gamma. SR1664 SRs 1664 SR-1664 Cdks five potent fluids retention weight gains inhibiting bones formations phosphorylation anti-diabetic |
Gene, Accession, CAS # | CAS: 1338259-05-4 |
Catalog # | 11086-5 |
Price | |
Order / More Info | SR 1664 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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