| 产品详情 |
| Edit |   |
|---|
| Product Name | SR 1001 |
|---|
| Description | A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs at 5 µM; 25 mg/kg twice/day delays onset and severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | inflammation autoimmune diseases RORα RORγ retinoic-acid-receptor-related orphans receptors IL-17 TH17 cells ligands mutiple sclerosis MS agonists differentiation PBMCs inhibits inhibitors inhibition splenocytes NCoR SR1001 SR-1001 |
|---|
| Gene, Accession, CAS # | CAS: 1335106-03-0 |
|---|
| Catalog # | 10922-5 |
|---|
| Price | |
|---|
| Order / More Info | SR 1001 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|