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| Product Name | SR 1001 |
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| Description | A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs at 5 µM; 25 mg/kg twice/day delays onset and severity of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | inflammation autoimmune diseases RORα RORγ retinoic-acid-receptor-related orphans receptors IL-17 TH17 cells ligands mutiple sclerosis MS agonists differentiation PBMCs inhibits inhibitors inhibition splenocytes NCoR SR1001 SR-1001 |
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| Gene, Accession, CAS # | CAS: 1335106-03-0 |
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| Catalog # | 10922-25 |
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| Price | |
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| Order / More Info | SR 1001 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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