| 产品详情 |
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| Product Name | CMPF |
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| Description | Furan fatty acids are unique, naturally occurring lipids that are found in significant amounts in dietary phospholipids, such as in salmon roe.{13184} CMPF is an endogenous metabolite of furan fatty acids in humans. CMPF is highly albumin-bound and accumulates in the serum of uremic patients to concentrations in excess of 0.2 mM. Its primary effect is to inhibit cellular transport and subsequent deiodination of thyroxine (T4).{13104,13105} CMPF is tightly bound to albumin but only moderately inhibits T4 binding in a direct manner (10-14% at 0.3 mM). However, CMPF effectively displaces competitive T4 binding molecules from albumin, such as acidic drugs and free fatty acids.{13105} Therefore, CMPF may indirectly influence T4 binding to albumin by increasing the serum concentration of competitive binding molecules, particularly free fatty acids such as oleic acid.{13105} |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | thyroxines T3 T4 furan fatty acids inactive primary secreted products thyroid glands converted active hormones triiodothyrodinine enzymes 5'-deiodinase albumin-bound furanoids accumulates serums uremic patients inhibits cellular transport subsequent deiodination displaces competitive binding molecules acidic drugs free oleic endocrinology |
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| Gene, Accession, CAS # | CAS: 86879-39-2 |
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| Catalog # | 10007133-500 |
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| Order / More Info | CMPF from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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