| 产品详情 |
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| Product Name | iCRT14 |
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| Description | An inhibitor of CRT (IC50 = 40.3 nM); inhibits β-catenin/Tcf4 binding (Kis = 53.51 µM); inhibits Notch, Hh, and JAK/STAT signaling (IC50s = 69.2, 194, and 70 nM, respectively); reduces proliferation and initial tumor growth rate in mouse xenografts of colon carcinoma (50 mg/kg i.p.); inhibits proliferation of leukemia cell lines; suppresses ATP-driven migration of the MCF-7 and MDA-MB-231 breast cancer cell lines |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | iCRT-14 Tcf-4 MCF7 MDAMB231 |
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| Gene, Accession, CAS # | CAS: 677331-12-3 |
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| Catalog # | 22132-5 |
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| Price | |
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| Order / More Info | iCRT14 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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