| 产品详情 |
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| Product Name | Treprostinil |
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| Description | Treprostinil is a stable analog of prostacyclin (Item No. 18220) that is used clinically for the treatment of PPH under the trade name Remodulin™. The structural modifications in treprostinil compared to prostacyclin increase the plasma half-life from 2 minutes to 34 and 85 minutes for intravenous and subcutaneous infusion of the drug, respectively.{13285} In addition to treprostinil's direct vasodilatory effects, it also inhibits inflammatory cytokine (TNFα, IL-1β, IL-6, GM-CF) production by human alveolar macrophages in the sub-micromolar range by preventing NF-κB translocation to the nucleus.{12665} |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | BW 15AU|LRX 15|Rumodolin|U-62840|Uniprost |
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| Gene, Accession, CAS # | CAS: 81846-19-7 |
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| Catalog # | 10162-10 |
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| Price | |
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| Order / More Info | Treprostinil from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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