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| Product Name | RU-SKI 43 (hydrochloride) |
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| Description | A cell-permeable inhibitor of Hhat (IC50 = 0.85 µM); blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a; inhibits both autocrine and paracrine Shh-induced activation of Gli-mediated transcription |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical inhibitor signal transduction cancer gene regulation inhibit hedgehog acyltransferase Hhat N-palmitoyltransferase Sonic Shh acylate signaling RUSKI43 RUSKI-43 RU-SKI-43 block palmitoylation cell permeable autocrine paracrine Shh-induced activation Gli-mediated transcription pancreatic cell Gli-1 Gli1 activation proliferation 1043797-53-0 |
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| Gene, Accession, CAS # | CAS: 1782573-67-4 |
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| Catalog # | 16972-10 |
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| Order / More Info | RU-SKI 43 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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