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| Product Name | Memantine (hydrochloride) |
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| Description | An NMDA receptor antagonist; blocks NMDA-induced currents in rat retinal ganglion cells by 90% at 12 µM; reverses I1PP2A-induced inhibition of dephosphorylation of tau194-207 in vitro; restores PP2A activity, decreases GSK-3β and Aβ levels in the hippocampus, cerebral cortex, and ventricular areas, and attenuates spatial learning and memory in the AAV1-I1PP2A rat model of Alzheimer's disease at 2 mg/kg; reduces responding on the ethanol-associated lever in a cue-induced ethanol seeking test in rats at 20 mg/kg; decreases secretion of MMP-9, degradation of collagen IV, the size of cerebral ischemia-induced brain infarcts, and neuronal cell death in a mouse model of focal cerebral ischemia, |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Akatinol|Axura|Ebix|Namenda|NSC 102290|SUN Y7017 |
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| Gene, Accession, CAS # | CAS: 41100-52-1 |
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| Catalog # | 14184-25 |
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| Order / More Info | Memantine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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