| 产品详情 |
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| Product Name | Amantadine (hydrochloride) |
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| Description | An NMDAR antagonist (IC50s = 0.93, 0.82, and 0.47 µM at -70 mV for NR1-1a/NR2A, NR1-1a/NR2B, and NR1-1a/NR2D subunit-containing recombinant receptors, respectively, expressed in HEK293 cells); blocks the influenza A M2 proton channel (IC50 = 16 µM for the recombinant channel expressed in Xenopus oocytes) and inhibits cytotoxicity induced by the influenza A strains H1N1 and H3N2 in MDCK cells (EC50s = 34 and 0.84 µM, respectively); improves the survival of mice infected with influenza A when administered 24 hours following viral challenge at a dose of 100 mg/kg per day; decreases L-DOPA-induced dyskinesia in a 6-OHDA hemi-parkinsonian mouse model at 40 mg/kg |
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| Size | 100 g |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Adamantylamine|Aminoadamantane|NSC 83653 |
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| Gene, Accession, CAS # | CAS: 665-66-7 |
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| Catalog # | 21364-100 |
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| Order / More Info | Amantadine (hydrochloride) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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