| 产品详情 |
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| Product Name | DC260126 |
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| Description | A FFAR1 (GPR40) antagonist that inhibits GPR40-mediated Ca2+ elevations stimulated by linoleic, oleic, palmitoleic, and lauric acid with IC50 values of 6.28, 5.96, 7.07, and 4.58 µM, respectively; inhibits glucose-stimulated insulin secretion, reduces blood insulin levels, improves insulin sensitivity, and decreases the rate of pancreatic β-cell apoptosis in obese diabetic db/db mice at 10 mg/kg |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | free fatty acid receptor GPR40 FFAR1 FFAR-1 GPR-40 DC-260126 calcium b-cell FFAR1/GPR40 |
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| Gene, Accession, CAS # | CAS: 346692-04-4 |
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| Catalog # | 19388-1 |
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| Order / More Info | DC260126 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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