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Product Name | Mutant IDH1-IN-1 |
Description | An inhibitor of mutant IDH1 (IC50s = 42, 4, and 80 nM for IDH1R132H/R132H, IDH1R132C/R132C, and IDH1R132H/WT, respectively, for conversion of α-KG to 2-HG); selective for IDH1 mutant conversion of α-KG to 2-HT over IDH1WT/WT conversion of isocitrate to α-KG (IC50 = 1,998 nM) and over IDH2 (IC50s = >10,000 nM); inhibits 2-HG production in vitro (IC50 = 81.5 nM), |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1355326-25-8 1648909-74-3 1648909-75-4 IDH1IN1 IDH-1 R-132H 132C αKG 2HG HEK-293 |
Gene, Accession, CAS # | CAS: 1355326-21-4 |
Catalog # | 18394-50 |
Price | |
Order / More Info | Mutant IDH1-IN-1 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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