| 产品详情 |
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| Antigenic Specificity | TNFRSF1B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TNFRSF1B Antibody is a Rabbit Polyclonal antibody against TNFRSF1B. The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. |
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| Immunogen | Recombinant protein of human TNFRSF1B. |
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| Other Names | CD120B; P75; TBPII; TNF-R-II; TNF-R75; TNFBR; TNFR2; TNFR80; P75tnfr; Tumor necrosis factor receptor 2; p80 TNF-alpha receptor; Etanercept; TNFR1B; TNFRSF1B; tumor necrosis factor receptor superfamily; member 1B |
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| Gene, Accession # | TNFRSF1B, Gene ID: 7133, SwissProt: P20333 |
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| Catalog # | abx001016 |
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| Price | |
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| Order / More Info | TNFRSF1B Antibody from ABBEXA |
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| Product Specific References | n/a |
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