产品详情 |
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Product Name | Goserelin (acetate) |
Description | A synthetic GNRH agonist; binds to the GNRHR (Ki = 1.6 nM in CHO cells expressing the human receptor); binds to mouse pituitary αT3-1 cells and human placenta (Kds = 2 and 580 nM, respectively) and increases intracellular calcium in αT3-1 cells; induces testosterone production in vitro within 4 h in rat Leydig cells (ED50 = 83 nM) but decreases testosterone plasma level in vivo in rats over a period of 2 to 24 weeks; inhibits tumor growth in a DU145 human prostate carcinoma mouse xenograft model (100 µg per day) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 65807-02-5 145781-92-6 zoladex Chinese hamster ovary αT31 DU-145 ICI118630 ICI 118630 2-(aminocarbonyl)hydrazide-6-[O-(1,1-dimethylethyl)-D-serine]-1-9-luteinizing hormone-releasing factor (swine), monoacetate |
Gene, Accession, CAS # | CAS: 145781-92-6 |
Catalog # | 24071-10 |
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Order / More Info | Goserelin (acetate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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