| 产品详情 |
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| Product Name | H3B-6527 |
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| Description | An FGFR4 inhibitor (IC50 = 50s = 320, 1,290, and 1,060 nM, respectively), as well as TAOK2, JNK2, and CSF1R (IC50s = 690, >10,000, and >10,000 nM, respectively); decreases cell growth (GI50 = 25 nM) and increases caspase-3/7 activity in Hep3B HCC cells; selectively inhibits cell growth in HCC cell lines that express high levels of FGF19; reduces tumor growth in a Hep3B HCC mouse xenograft model at 100 and 300 mg/kg |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | H-3B-6527 3B6527 H3B6527 FGFR-1 2 3 4 TAOK-2 JNK-2 CYP-7A1 ERK-1 2 Hep-3B FGF-19 PD0332991 JHH7 fibroblast growth factor |
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| Gene, Accession, CAS # | CAS: 1702259-66-2 |
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| Catalog # | 26072-1 |
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| Order / More Info | H3B-6527 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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