产品详情 |
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Antigenic Specificity | ITM2C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ITM2C Polyclonal Antibody. Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. |
Immunogen | n/a |
Other Names | BRI3, BRICD2C, E25, E25C, ITM3, BRICHOS domain containing 2C, cerebral protein 14, hRPC.1050_D_4, integral membrane protein 3, transmembrane protein BRI3 |
Gene, Accession # | Entrez: 81618; Uniprot: Q9NQX7 |
Catalog # | PA5-30838 |
Price | |
Order / More Info | ITM2C Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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