产品详情 |
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Product Name | Fenofibrate |
Description | A PPARα agonist (EC50s = 18 and 30 µM for mouse and human receptors, respectively, in a transactivation assay); selective for PPARα over PPARγ (EC50s = 300 and 200 µM for mouse and human receptors, respectively) and lacks activity at mouse and human PPARδ at 100 µM; reduces plasma levels of triglycerides, C-reactive protein, and MDA in mice with fructose-induced hypertriglycemia from 50-100 mg/kg; decreases cisplatin-induced glomerular and tubular atrophy and necrosis in rat kidney at 100 mg/kg; reduces the number of 4-NQO-induced pulmonary lesions in lung in TSOD mice |
Size | 50000 mg |
Concentration | n/a |
Applications | n/a |
Other Names | PPAR.alpha. PPARalpha peroxisome proliferator-activated receptors nuclear fibrate dyslipidemia FA b- beta-oxidation hypolipidemic atherosclerosis endocrinology |
Gene, Accession, CAS # | CAS: 49562-28-9 |
Catalog # | 10005368-50 |
Price | |
Order / More Info | Fenofibrate from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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