| 产品详情 |
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| Antigenic Specificity | MAP2K2 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. |
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| Immunogen | Purified recombinant fragment of human MAP2K2 expressed in E. Coli. |
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| Other Names | MAP2K2; mitogen-activated protein kinase kinase 2; MAPKK2; MEK2; MKK2; PRKMK2; ERK activator kinase 2; MAP kinase kinase 2; MAPK/ERK kinase 2; dual specificity mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45 |
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| Gene, Accession # | Gene ID: 5605, SwissProt: P36507 |
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| Catalog # | abx011107 |
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| Price | |
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| Order / More Info | MAP2K2 Antibody from ABBEXA |
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| Product Specific References | n/a |
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