产品详情 |
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Product Name | DCP-LA |
Description | An activator of PKCε; activates PKCε with a >7-fold stronger potency over PKCα, βI, βII, γ, δ, μ, η, and ζ in a cell-free assay; activates PKC in PC12 cells in a concentration-dependent manner; decreases intracellular levels of Aβ in Neuro2 neuroblastoma cells transfected with human APPSwe/PS1Δ9; stimulates hippocampal glutamate release, striatal dopamine release, and hypothalamic serotonin release in rat brain slices in a PKC- and α7-containing nAChR- dependent manner; prevents synaptic loss and amyloid plaque formation and decreases escape latency in the Morris water maze in the 5XFAD transgenic mouse model of Alzheimer's disease at 3 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | FR 236924 |
Gene, Accession, CAS # | CAS: 28399-31-7 |
Catalog # | 21375-5 |
Price | |
Order / More Info | DCP-LA from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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