| 产品详情 |
| Edit |   |
|---|
| Product Name | MitoCheck® Complex II Activity Assay Kit |
|---|
| Description | Complex II (succinate dehydrogenase/co-enzyme Q reductase) is one of the major sites of electron entry into the mitochondrial electron transport chain (ETC). Complex II catalyzes the oxidation of succinate to fumarate, and in the process reduces ubiquinone (Q) to ubiquinol (QH2). Ultimately, oxidation of succinate will lead to reduction of O2, the terminal step in mitochondrial respiration. Cayman's MitoCheck® Complex II Activity Assay allows for the activity of complex II to be determined without the need to isolate mitochondria or pre-incubate with antibodies. As complex II oxidizes succinate, electrons are passed to an analog of ubiquinone and then on to DCPIP, which, when oxidized, absorbs in the 600 nm range. The absorbance of DCPIP will decrease upon reduction. Thus, Complex II activity is measured as a decrease in absorbance at 600 nm over time. |
|---|
| Size | 96 well |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | kits assays measures measurements two 2 succinates dehydrogenases dehydrogenase/co-enzyme Q CoQ10 reductases sites electrons entry mitochondrial mitochondrias transports chains ETCs catalyzes oxidations fumarates reduces reductions ubiquinones ubiquinol QH2 oxygens O2 terminal steps respirations dysfunctions inhibits inhibitors inhibitions oncogenesis cancers inhibitory effects dehydrogenases atpenin A5 2-Thenoyltrifluoroacetone TTFA malonates isolates isolations DCPIP complexes rotenone antimycin A potassium cyanides KCN |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 700940-96WELLS |
|---|
| Price | |
|---|
| Order / More Info | MitoCheck® Complex II Activity Assay Kit from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|