| 产品详情 |
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| Product Name | Almotriptan (malate) |
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| Description | An agonist of 5-HT1B and 5-HT1D receptors (IC50s = 12 and 13 nM, respectively, in a radioligand binding assay); selective for human 5-HT1B and 5-HT1D receptors over rat 5-HT1A and human 5-HT2A and 5-HT4 receptors (IC50s = 0.85, 25.1, and 140 µM, respectively); induces contractions in isolated canine saphenous veins (EC50 = 394 nM) but not isolated rabbit renal or mesenteric arteries; increases carotid vascular resistance in anesthetized cats (ED100 = 11 µg/kg, i.v.) without increasing blood pressure or heart rate |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Almotrip forte|LAS 31416 D,L-malate acid|PNU 180638E |
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| Gene, Accession, CAS # | CAS: 181183-52-8 |
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| Catalog # | 25646-50 |
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| Order / More Info | Almotriptan (malate) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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