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Product Name | Almotriptan (malate) |
Description | An agonist of 5-HT1B and 5-HT1D receptors (IC50s = 12 and 13 nM, respectively, in a radioligand binding assay); selective for human 5-HT1B and 5-HT1D receptors over rat 5-HT1A and human 5-HT2A and 5-HT4 receptors (IC50s = 0.85, 25.1, and 140 µM, respectively); induces contractions in isolated canine saphenous veins (EC50 = 394 nM) but not isolated rabbit renal or mesenteric arteries; increases carotid vascular resistance in anesthetized cats (ED100 = 11 µg/kg, i.v.) without increasing blood pressure or heart rate |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Almotrip forte|LAS 31416 D,L-malate acid|PNU 180638E |
Gene, Accession, CAS # | CAS: 181183-52-8 |
Catalog # | 25646-10 |
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Order / More Info | Almotriptan (malate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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