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Product Name | Cirazoline (hydrochloride) |
Description | An α1-adrenergic receptor agonist (Kis = 120, 960, and 660 nM at α1A-, α1B-, and α1D-ARs, respectively); a full agonist at α1A- and a partial agonist at α1B- and α1D-ARs (EC50s = 70.7, 79.4, and 239.8 nM, respectively); decreases blood pressure when microinjected into the NRL of the brainstem of anesthetized cats at doses ranging from 0.01-1 µg/kg; enhances spatial memory and reduces depressive- and anxiety-like behavior in mice when administered at a concentration of 10 mg/L in drinking water; enhances memory in aged rhesus monkeys at high doses of 1-10 µg/kg but impairs performance at lower doses of 0.01-1 µg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 59939-16-1 LD3098 LD-3098 α-1 1A 1B 1D 2 pA-2 α1AR α1DAR α1BAR α2AR Chinese hamster ovary |
Gene, Accession, CAS # | CAS: 40600-13-3 |
Catalog # | 21791-10 |
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Order / More Info | Cirazoline (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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