产品名称 AUDA from CAYMAN CHEMICAL COMPANY
产品货号 10007927-50
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 CAYMAN CHEMICAL COMPANY
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Product NameAUDA
DescriptionAUDA is an inhibitor of sEH exhibiting IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively.{14064} In angiotensin-infused rats, a dose of 25 mg/l AUDA administered in drinking water decreased mean arterial blood pressure from 161 ± 4 mmHg to 140 ± 5 mmHg. This hypotensive effect was accompanied by an increase in urinary epoxide-to-diol ratios.{14065} AUDA activates PPARα 3-fold at a concentration of 10 µM but exhibits no affect on PPAR.delta. or PPARγ.{13447}
Size50 mg
Concentrationn/a
Applicationsn/a
Other Namesepoxides hydrolases hypertension dihydroxy-eicosatrienoic acids DHETs 11(12)-EETs 14(15)-EETs blood pressure soluble sEH inhibits inhibitors inhibition peroxisome proliferator-activated receptors PPARalpha PPAR.alpha. DiHETrEs EpETrEs endocrinology
Gene, Accession, CAS #CAS: 479413-70-2
Catalog #10007927-50
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Order / More InfoAUDA from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
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