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| Product Name | PAD2 Inhibitor Screening Assay Kit (AMC) |
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| Description | PAD2 is a guanidino-modifying enzyme that catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. This enzyme has been implicated in several diseases, including rheumatoid arthritis (RA), retinal degeneration, and certain cancers. PAD2 has been shown to modify vimentin, fibrinogen, and β/γ-actin. Extracellular levels of PAD2 are increased in the lungs of smokers, providing a link between smoking as a risk factor for RA and anti-citrullinated protein antibodies among RA patients. Cayman's PAD2 Inhibitor Screening Assay Kit (AMC) provides a convenient method for screening human PAD2 inhibitors. |
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| Size | 96 well |
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| Concentration | n/a |
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| Applications | High-Throughput Screening |
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| Other Names | PAD-H19|PADI2|Peptidylarginine Deiminase 2|Protein Arginine Deiminase 2 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 701390-96WELLS |
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| Order / More Info | PAD2 Inhibitor Screening Assay Kit (AMC) from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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