| 产品详情 |
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| Antigenic Specificity | NDUFV1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN) and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10, 000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This NDUFV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human NDUFV1. |
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| Immunogen | Human NDUFV1. |
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| Other Names | NADH dehydrogenase (ubiquinone) flavoprotein 1; 51kDa; NDUFV1; CI-51kD; UQOR1; NADH dehydrogenase [ubiquinone] flavoprotein 1; mitochondrial; Complex I-51kD; NADH dehydrogenase flavoprotein 1; NADH-ubiquinone oxidoreductase 51 kDa subunit; CI-51K; Complex I 51 kda subunit; CI51KD; Complex I 51kDa subunit |
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| Gene, Accession # | SwissProt: P49821 |
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| Catalog # | abx031001 |
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| Price | |
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| Order / More Info | NDUFV1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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