| 产品详情 |
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| Antigenic Specificity | MRVI1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MRVI1 Polyclonal Antibody. This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is downregulated during lymphoid differentiation. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation, and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, few of which initiate transl |
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| Immunogen | n/a |
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| Other Names | IRAG, JAW1L, IP3R-associated cGMP kinase substrate, JAW1-related protein MRVI1, inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate, protein MRVI1 |
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| Gene, Accession # | Entrez: 10335; Uniprot: Q9Y6F6 |
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| Catalog # | PA5-52592 |
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| Price | |
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| Order / More Info | MRVI1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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