产品详情 |
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Antigenic Specificity | TRPV6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | lyophilized |
Applications | Immunohistochemistry: 1:300-1:3000, Western Blot: 1:300-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRPV6 Polyclonal Antibody. Calcium selective cation channel probably involved in Ca(2+) uptake in various tissues, including Ca(2+) reabsorption in intestine. The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification. Inactivation includes both, a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating. Interacts with TRPV5, heterotetramer. Expressed in duodenu |
Immunogen | n/a |
Other Names | Transient receptor potential cation channel subfamily V member 6, TrpV6, Epithelial calcium channel 2, ECaC2, Calcium transport protein 1, CaT1, Trpv6 |
Gene, Accession # | Entrez: 114246; Uniprot: Q9R186 |
Catalog # | OSR00076W |
Price | |
Order / More Info | TRPV6 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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