| 产品详情 |
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| Antigenic Specificity | TIA-1 |
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| Clone | OTI1C8 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TIA-1 Monoclonal Antibody (OTI1C8). FAS, also referred to as CD95 or APO-1, is a type I transmembrane protein that plays a central role mediating viral immunity. TIA-1 and TIAR are two closely related proteins that possess three RRMs (RNA recognition motifs), designated RRM 1, 2 and 3. Although both TIA-1 and TIAR are thought to function as mediators of apoptotic cell death, their specific roles in such pathways are unknown. Unlike TIA-1, which is found in the granules of cytotoxic lymphocytes, TIAR expression is limited to the nucleus and found in a much broader range of cells including, but not limited to, cells of hematopoietic origin. TIAR is translocated to the cytoplasm shortly after FAS ligation and this event immediately proceeds th |
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| Immunogen | n/a |
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| Other Names | Cytotoxic granule associated RNA binding protein 1;Cytotoxic granule associated RNA binding protein;mTIA-1;Nucleolysin TIA 1 isoform p40;Nucleolysin TIA-1 isoform p40;Nucleolysin TIA1 isoform p40;p40 TIA 1;p40-TIA-1 (containing p15-TIA-1);p40-TIA-1;RNA binding protein TIA 1;RNA binding protein TIA1;RNA-binding protein TIA-1;T-cell-restricted intracellular antigen-1;TIA 1;TIA 1 cytotoxic granule associated RNA binding protein;Tia;TIA-1;TIA1;TIA1 cytotoxic granule associated RNA binding protein;TIA1 cytotoxic granule associated RNA binding protein like 1;TIA1 protein;TIA1_HUMAN;TIAL1;TIAR; |
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| Gene, Accession # | Entrez: 7072; Uniprot: P31483 |
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| Catalog # | MA5-26475 |
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| Price | |
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| Order / More Info | TIA-1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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