| 产品详情 |
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| Product Name | CCT137690 |
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| Description | A potent inhibitor of Aurora kinases (IC50s = 15, 25 and 19 nM for Aurora A, B, and C, respectively); also inhibits FLT3 as well as the constitutively active FLT3-ITD form (IC50s = 1.2 and 4.9 nM, respectively); orally bioavailable, inhibiting the growth of SW620 colon carcinoma xenografts in mice |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | biochemical cancer kinase protein signal transduction receptor biochemistry intracellular signaling CCT 13769 CCT-13769 inhibitor inhibit inhibition Aurora A B C tyrosine FLT3 FLT3-ITD growth SW620 colon carcinoma xenografts mice body weight loss MYCN neuroblastoma cell N-myc expression proliferation D835Y mutation colorectal radiotherapy |
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| Gene, Accession, CAS # | CAS: 1095382-05-0 |
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| Catalog # | 15552-10 |
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| Order / More Info | CCT137690 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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