| 产品详情 |
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| Antigenic Specificity | Skeletal Muscle Actin |
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| Clone | 5C5.F8.C7 (alpha-Sr-1) |
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| Host Species | Mouse |
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| Reactive Species | amphibian, bovine, guinea pig, human, mouse, ovine, rabbit, rat |
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| Isotype | IgM, kappa |
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| Format | purified |
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| Size | 500 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: Assay Dependent, Immunohistochemistry (Paraffin): 1:200-1:400 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Skeletal Muscle Actin Monoclonal Antibody (5C5.F8.C7 (alpha-Sr-1)). The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. |
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| Immunogen | n/a |
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| Other Names | actin, alpha skeletal muscle, alpha skeletal muscle actin, alpha-actin-1 |
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| Gene, Accession # | Entrez: 100009271, 100009506, 100716933, 100722917, 101107662, 101121051, 11459, 11475, 281592, 29437, 515610, 58, 59, 81633; Uniprot: P62736, P62737, P62738, P62739, P68133, P68134, P68135, P68136, P68138 |
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| Catalog # | MA5-12542 |
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| Price | |
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| Order / More Info | Skeletal Muscle Actin Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 12460205, 15363044, 16585386, 17853405 |
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