| 产品详情 |
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| Antigenic Specificity | SKAP55 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 5 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SKAP55 Polyclonal Antibody. Src kinase-associated phosphoprotein of 55 kDa (SKAP55) is expressed as a constitutively tyrosine phosphorylated 55-kD adapter protein that positively regulates TCR signaling. SKAP55 has also been shown to enhance adhesion to fibronectin and ICAM1, colocalize with F-actin at the T cell-antigen-presenting cell synapse and promotes the clustering of LFA1 and TCR ligation. TCR engagement induces the translocation of SKAP55 to lipid rafts, where the interactions with Fyn take place. CD45 also plays a very important role in SKAP55/TCR-mediated signaling. SKAP55 involvement in the TCR signaling pathway is the subject of current research in murine as well as human models. |
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| Immunogen | n/a |
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| Other Names | SCAP1, SKAP55 adaptor protein, SRC family associated phosphoprotein 1, SRC kinase associated phosphoprotein 55 kD |
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| Gene, Accession # | Entrez: 8631; Uniprot: Q86WV1 |
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| Catalog # | PA1-525 |
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| Price | |
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| Order / More Info | SKAP55 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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