| 产品详情 |
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| Antigenic Specificity | VEGF Receptor 3 |
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| Clone | AFL4 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2a, kappa |
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| Format | unconjugated, functional grade |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | Control: Assay-Dependent, Flow Cytometry: Assay-Dependent, Functional Assay: Assay-Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | VEGF Receptor 3 Monoclonal Antibody (AFL4), Functional Grade, eBioscience™. Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the deve |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 14257; Uniprot: P35917 |
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| Catalog # | 16-5988-85 |
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| Price | |
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| Order / More Info | VEGF Receptor 3 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 17438136, 20584329, 22848434, 26779981, 27023566, 27926858 |
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