产品详情 |
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Antigenic Specificity | VEGF Receptor 2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:10-1:500, Immunoprecipitation: 2-5 µL, Western Blot: 1:2000-1:10,000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VEGF Receptor 2 Polyclonal Antibody. VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signaling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity. |
Immunogen | n/a |
Other Names | 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, sVEGFR-2, CD309, KDR |
Gene, Accession # | Entrez: 16542, 3791; Uniprot: P35918, P35968 |
Catalog # | PA3-16624 |
Price | |
Order / More Info | VEGF Receptor 2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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