产品详情 |
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Antigenic Specificity | TOB2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TOB2 Polyclonal Antibody. TOB2 is a 344 amino acid rich novel member of the Tob/BTG1 anti-proliferative family of proteins characterized by similarities in their N-terminal BTG/Tob homology domains. This anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases and is involved in cell cycle regulation through interaction with Caf1, a component of the CCR4 transcription factor complex that associates with cyclin-dependent kinases. Recent reports suggest that TOB2 plays important roles in spermatogenesis, embryonic dorsoventral patterning, osteogenesis, T-cell activation, learning and memory and acts primarily as a transcriptional repressor in several signaling pathways. TOB2, a signaling protein, may participate i |
Immunogen | n/a |
Other Names | TOB4; TOBL; TROB2; protein Tob2; protein Tob4; transducer of erbB-2 2 |
Gene, Accession # | Entrez: 10766; Uniprot: Q14106 |
Catalog # | PA5-64968 |
Price | |
Order / More Info | TOB2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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