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| Antigenic Specificity | TOB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50 - 1:200 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TOB1 Polyclonal Antibody. This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcript |
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| Immunogen | n/a |
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| Other Names | APRO6; MGC104792; MGC34446; PIG49; TOB; TROB; TROB1 |
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| Gene, Accession # | Entrez: 10140; Uniprot: P50616 |
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| Catalog # | PA5-65480 |
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| Price | |
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| Order / More Info | TOB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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